| ABBEY ROAD HOSPICE, LLC | Columbia | — | 2024 | $1.5M | +7.3% | 143d |
| AFFINITY HOSPICE | Greenville | — | 2024 | $0.4M | +9.8% | 1055d |
| AGAPE CARE SOUTH CAROLINA II | Spartanburg | — | 2024 | $89.8M | -60.6% | 26d |
| AGAPE HOSPICE OF THE LOWCOUNTRY | North Charleston | — | 2024 | $59.3M | -76.7% | 35d |
| ALL SEASONS HEALTHCARE, INC | Irmo | — | 2024 | $4.3M | +7.2% | 20d |
| AMEDISYS HOSPICE OF SOUTH CAROLINA | Florence | — | 2024 | $36.7M | +11.2% | — |
| ANGELIC HEALTH OF SC LLC | Myrtle Beach | — | 2024 | $3.0M | +7.0% | 0d |
| ARCADIA HOSPICE, LLC | Hardeeville | — | 2022 | $0.2M | — | — |
| ARDENT HOSPICE & PALLIATIVE CARE OF SC, INC | Murrells Inlet | — | 2024 | $1.3M | -18.6% | — |
| BERNARDO HOSPICE CARE | Newberry | — | 2024 | $0.4M | — | 39d |
| BON SECOURS HOSPICE BY COMPASSUS-GAFFNEY | Gaffney | — | 2024 | $1.2M | -12.7% | — |
| BROOKDALE HOSPICE GREENVILLE | — | — | 2022 | $0.3M | -3.7% | — |
| CARIS HEALTHCARE COLUMBIA | Columbia | — | 2024 | $12.4M | +53.9% | 632d |
| COMPASSIONATE CARE HOSPICE OF SOUTH CAROLINA, LLC | West Colimbia | — | 2024 | $12.6M | +5.2% | — |
| COMPASSUS-CHARLESTON | Ridgeland | — | 2024 | $2.3M | +11.1% | — |
| CRESCENT HOSPICE | Bluffton | — | 2024 | $8.9M | -20.8% | 9d |
| CRESCENT HOSPICE, INC | Columbia | — | 2024 | $33.9M | +19.3% | 9d |
| DIVINE HOSPICE, LLC | Anderson | — | 2024 | $2.1M | -2.7% | 840d |
| EDISTO HOME CARE & HOSPICE | Orangeburg | — | 2024 | $3.9M | +20.0% | 32d |
| EMPYREAN HOSPICE OF SOUTH CAROLINA | Aiken | — | 2024 | $5.4M | -4.9% | — |
| ENHABIT HOSPICE | Aiken | — | 2024 | $2.7M | +14.8% | — |
| EPIC CARE HEALTH LLC | Fort Mill | — | 2024 | $1.3M | +7.1% | 54d |
| FAMILY HOSPICE OF GREENVILLE LLC | Greenville | — | 2024 | $4.9M | -30.2% | 80d |
| FRIENDS OF CAROLINE HOSPICE OF BEAUFORT, INC | Ridgeland | — | 2024 | $2.1M | -52.6% | 18d |
| Gentiva | Aiken | — | 2024 | $21.2M | +20.6% | — |
| GENTIVA | Anderson | — | 2024 | $6.4M | +21.6% | — |
| GHC HOSPICE | Ridgeland | — | 2023 | $0.1M | -33.0% | 16d |
| GROVE PARK PHARMACY HOSPICE | Orangeburg | — | 2024 | $2.4M | +28.4% | 74d |
| HADORA HOSPICE OF THE CAROLINAS | Columbia | — | 2025 | $0.7M | +6.0% | 26d |
| HANDS OF HOPE | Columbia | — | 2024 | $7.3M | — | 76d |
| HEART OF HOSPICE LLC | Columbia | — | 2024 | $7.3M | +6.6% | — |
| Heart of Hospice Lowcountry | — | — | 2023 | $0.9M | -40.7% | — |
| HEART OF HOSPICE UPSTATE | Spartanburg | — | 2024 | $-0.3M | -94.7% | — |
| HEARTLAND HOSPICE SERVICES | Myrtle Beach | — | 2024 | $3.7M | +23.0% | — |
| HEARTLAND HOSPICE SERVICES - GREENVILLE | Simpsonville | — | 2024 | $2.8M | -19.0% | — |
| HELPING HANDS HOSPICE OF SOUTH CAROLINA LLC | Aiken | — | 2024 | $0.0M | -26.0% | 20d |
| HOMEBRIDGE HOSPICE OF AAMC | Abbeville | — | 2024 | $0.9M | +25.3% | — |
| HOMESTEAD HOSPICE OF AUGUSTA, LLC | Myrtle Beach | — | 2024 | $1.9M | +12.7% | 0d |
| HOMESTEAD HOSPICE OF CHARLESTON, LLC | Summerville | — | 2024 | $2.3M | +11.0% | — |
| HOMESTEAD HOSPICE OF COLUMBIA, LLC | Irmo | — | 2024 | $3.4M | +2.0% | — |
| HOSPICE & PALLIATIVE CARE PALMETTO REGION | Fort Mill | — | 2024 | $8.1M | +86.3% | — |
| Hospice & Palliative Care Palmetto Region- Greenville County | Greenville | — | 2024 | $12.9M | -24.5% | 68d |
| HOSPICE AND COMMUNITY CARE | Rock Hill | — | 2025 | $5.1M | -17.6% | 269d |
| HOSPICE AND PALLIATIVE CARE OF THE PIEDMONT | Greenwood | — | 2025 | $5.1M | -77.4% | 41d |
| HOSPICE CARE OF THE LOWCOUNTRY | Bluffton | — | 2024 | $5.5M | -19.8% | 228d |
| HOSPICE OF CHARLESTON | North Charleston | — | 2024 | $4.9M | +20.2% | — |
| HOSPICE OF SCOTLAND COUNTY, INC | Bennettsville | — | 2024 | $0.7M | +0.9% | 159d |
| HOSPICE OF THE UPSTATE, INC | Anderson | — | 2024 | $11.5M | -17.0% | 124d |
| HOSPICE SERVICES OF SC, LLC | North Augusta | — | 2024 | $1.3M | +19.3% | 45d |
| INTERIM HEALTH CARE HOSPICE OF CHARLESTON | North Charleston | — | 2024 | $2.1M | -9.2% | 67d |
| INTERIM HEALTH CARE OF THE TRIAD, INC | Rock Hill | — | 2024 | $0.6M | +19.6% | — |
| INTERIM HEALTHCARE OF THE UPSTATE HOSPICE | Greenville | — | 2024 | $17.9M | -8.6% | 86d |
| INTREPID USA HOSPICE-LOW COUNTRY | — | — | 2024 | $3.9M | +17.5% | 1d |
| KINDRED HOSPICE | Spartanburg | — | 2024 | $10.0M | +20.0% | — |
| LIGHTHOUSE HOSPICE GROUP, LLC | Irmo | — | 2024 | $1.9M | +15.9% | 51d |
| LOWER CAPE FEAR LIFECARE | Myrtle Beach | — | 2025 | $3.1M | +94.4% | — |
| LUTHERAN HOSPICE | White Rock | — | 2025 | $9.4M | +8.9% | 0d |
| MEDICAL SERVICES OF AMERICA HOSPICE OF THE LOWCOUN | Ridgeland | — | 2025 | $1.2M | -49.3% | 101d |
| MEDICAL SERVICES OF AMERICA HOSPICE OF THE UPSTATE | Greenville | — | 2025 | $4.6M | +12.6% | 101d |
| MEDICAL SERVICES OF AMERICA HOSPICE-COLUMBIA | Columbia | — | 2025 | $8.6M | -6.7% | 101d |
| MUSC Health Hospice at Home by Bayada-Charleston | Charleston | — | 2024 | $2.4M | -21.1% | 224d |
| PATHWAY HOSPICE LLC | Greenville | — | 2024 | $3.6M | +12.7% | 82d |
| PATRIOT HOSPICE | Easley | — | 2024 | $14.6M | +5.9% | 23d |
| PRISMA HEALTH HOSPICE MIDLANDS | Columbia | — | 2025 | $8.2M | +17.6% | — |
| PRISMA HEALTH HOSPICE OF THE FOOTHILLS | Seneca | — | 2025 | $9.6M | -12.2% | 3d |
| PRISMA HEALTH TUOMEY HOSPICE | Sumter | — | 2025 | $2.0M | -17.5% | — |
| PROMEDICA HOSPICE-CHARLESTON | Charleston | — | 2024 | $3.1M | +8.1% | — |
| PROVIDENCE HOSPICE LLC | Rock Hill | — | 2024 | $10.8M | -28.1% | 4d |
| PRUITTHEALTH HOSPICE-BEAUFORT | Bluffton | — | 2025 | $1.1M | — | — |
| PRUITTHEALTH HOSPICE- CHARLESTON | Ladson | — | 2025 | $3.4M | -93.7% | — |
| PRUITTHEALTH HOSPICE- COLUMBIA | Columbia | — | 2025 | $11.9M | -28.1% | 0d |
| REST ASSURED FAMILY SERVICES | — | — | 2022 | $0.0M | -59.4% | 16d |
| RIVERVIEW HOSPICE AND PALLIATIVE CARE,LLC | Rock Hill | — | 2024 | $0.2M | +6.4% | 65d |
| ST JOSEPH HOSPICE LLC | North Augusta | — | 2024 | $0.3M | -83.3% | 4d |
| THREE OAKS HOSPICE | Columbia | — | 2024 | $5.7M | +20.4% | 397d |
| TIDELANDS COMMUNITY HOSPICE/TIDELANDS COMMUNITY HO | Georgetown | — | 2024 | $4.1M | -3.5% | 200d |
| TRADITIONS HEALTH | — | — | 2024 | $2.3M | -74.8% | — |
| TRADITIONS HEALTH OF GREENVILLE | Greenville | — | 2024 | $2.8M | -15.2% | 0d |
| TRANSITIONS HOSPICE CARE OF GEORGIA, INC | Summerville | — | 2024 | $0.7M | -74.5% | 2d |
| UNITED HOSPICE OF THE PEE DEE | Florence | — | 2025 | $2.1M | -76.2% | — |
| V Care Hospice, LLC | Greer | — | 2025 | $3.9M | +13.2% | 28d |
| WREN HOSPICE, LLC | Greer | — | 2024 | $4.7M | -20.8% | 2d |
