| CENTRAL COLUMBIA KIDNEY CENTER | Columbia | — | 2024 | $3.4M | +2.1% | 6d |
| Clinton Dialysis Clinic | Clinton | — | 2024 | $2.7M | +8.9% | 16d |
| COLUMBIA NORTHEAST KIDNEY CENTER | Columbia | — | 2024 | $4.4M | +22.0% | 21d |
| DaVita Aiken Dialysis | Aiken | — | 2024 | $2.7M | -1.9% | — |
| DaVita Allendale County Dialysis | Fairfax | — | 2024 | $2.9M | -4.0% | — |
| DaVita Bluffton Dialysis | Bluffton | — | 2024 | $3.9M | +22.3% | — |
| DaVita Boiling Springs Dialysis | Boiling Springs | — | 2024 | $4.4M | +26.0% | — |
| DaVita Central Bamberg Dialysis | Bamberg | — | 2024 | $2.9M | +34.5% | — |
| DaVita Charles Towne Dialysis | Charleston | — | 2024 | $2.8M | +8.2% | — |
| DaVita Charles Towne Home Program | Charleston | — | 2024 | $2.1M | +19.1% | — |
| DaVita Coronaca Home Dialysis | Greenwood | — | 2024 | $2.3M | +26.9% | — |
| DaVita Cypress Gardens Dialysis | Sumter | — | 2024 | $1.9M | -9.0% | — |
| DaVita Cypress Gardens HT at Home | Sumter | — | 2024 | $0.5M | -33.4% | — |
| DaVita Faber Place Dialysis | Charleston | — | 2024 | $2.0M | -20.9% | — |
| DaVita Flower Town Home Training | Summerville | — | 2024 | $2.3M | +19.5% | — |
| DaVita Forest Acres Dialysis | Columbia | — | 2024 | $3.9M | +13.4% | — |
| DaVita Fort Mill Dialysis | Fort Mill | — | 2024 | $3.6M | +6.7% | — |
| DaVita Fountain Inn Dialysis | Fountain Inn | — | 2024 | $1.7M | +2.7% | — |
| DaVita Goose Creek Dialysis | Goose Creek | — | 2024 | $2.9M | -13.6% | — |
| DaVita Greenwood Dialysis | Greenwood | — | 2024 | $8.5M | +23.1% | — |
| DaVita Greer Kidney Center | Greer | — | 2024 | $2.1M | +2.6% | — |
| DaVita Greer South Dialysis | Greer | — | 2024 | $3.4M | +16.3% | — |
| DaVita Greer South Home Training (PD) | Greer | — | 2024 | $2.7M | +38.4% | — |
| DaVita Jedburg Dialysis | Summerville | — | 2024 | $3.1M | +6.4% | — |
| DaVita Lancaster SC Dialysis | Lancaster | — | 2024 | $5.4M | +19.7% | — |
| DaVita Longs Dialysis | Longs | — | 2024 | $2.2M | +1.4% | — |
| DaVita Marion Towne Dialysis | Marion | — | 2024 | $1.6M | -7.6% | — |
| DaVita Market Commons Dialysis Center | Myrtle Beach | — | 2024 | $5.0M | +18.8% | — |
| DaVita McColl Dialysis | Mccoll | — | 2024 | $2.6M | +10.8% | — |
| DaVita Myrtle Beach Dialysis | Myrtle Beach | — | 2024 | $2.6M | +12.5% | — |
| DaVita North Charleston Dialysis | North Charleston | — | 2024 | $3.5M | -8.7% | — |
| DaVita North Orangeburg Dialysis | Orangeburg | — | 2024 | $7.4M | +18.9% | — |
| DaVita Pageland Dialysis | Pageland | — | 2024 | $1.6M | -3.5% | — |
| DaVita Palmetto Dialysis | Clinton | — | 2024 | $2.3M | -1.3% | — |
| DaVita Pamplico Dialysis | Florence | — | 2024 | $4.4M | +21.7% | — |
| DaVita Pendleton Dialysis | Pendleton | — | 2024 | $1.1M | -1.8% | — |
| DaVita Saluda River Dialysis | Piedmont | — | 2024 | $3.4M | +16.1% | — |
| DaVita Santee Dialysis | Santee | — | 2024 | $2.7M | +14.7% | — |
| DaVita Upstate Dialysis Center | Greenville | — | 2024 | $7.0M | +14.7% | — |
| DaVita Walterboro Dialysis | Walterboro | — | 2024 | $3.8M | +3.5% | — |
| DaVita Wofford at Home | Spartanburg | — | 2024 | $2.9M | +6.9% | — |
| DCI - LANDRUM | Landrum | — | 2025 | $1.0M | +2.3% | 481d |
| DCI ARCHDALE | Charleston | — | 2025 | $4.5M | -4.2% | 193d |
| DCI EAST COOPER | Mount Pleasant | — | 2025 | $1.7M | -5.8% | — |
| DCI EAST SPARTANBURG | Spartanburg | — | 2025 | $5.6M | +7.1% | 676d |
| DCI GAFFNEY | Gaffney | — | 2025 | $3.8M | +12.8% | 417d |
| DCI GOOSE CREEK INC | Goose Creek | — | 2025 | $2.4M | +8.3% | 152d |
| DCI JAMES ISLAND | Charleston | — | 2025 | $2.0M | +0.2% | — |
| DCI Summerville-Nexton | Summerville | — | 2025 | $0.8M | -71.0% | — |
| DCI UNION | Union | — | 2025 | $2.0M | +1.7% | 112d |
| DCI WEST ASHLEY | Charleston | — | 2025 | $2.6M | -12.9% | — |
| DCI WEST SPARTANBURG | Spartanburg | — | 2025 | $3.7M | +5.7% | 425d |
| DCI Woodruff | Woodruff | — | 2025 | $1.4M | +0.1% | — |
| Dentsville Kidney Center | Columbia | — | 2024 | $2.0M | -4.7% | 3d |
| DIALYSIS 422511 | — | — | 2023 | $1.0M | -21.3% | — |
| DIALYSIS 422524 | — | — | — | — | — | — |
| DIALYSIS 422563 | — | — | 2023 | $0.9M | -18.4% | 87d |
| DIALYSIS 422565 | — | — | 2023 | $1.7M | -13.1% | — |
| DIALYSIS 422567 | — | — | 2022 | $2.3M | -3.7% | — |
| DIALYSIS 422573 | — | — | 2022 | $0.0M | -20.4% | — |
| DIALYSIS 422586 | — | — | 2022 | $1.3M | -63.1% | — |
| DIALYSIS 422588 | — | — | — | — | — | — |
| DIALYSIS 422590 | — | — | 2024 | $1.8M | -17.5% | — |
| DIALYSIS 422599 | — | — | 2022 | $0.3M | -73.3% | — |
| DIALYSIS 422626 | — | — | 2021 | $1.1M | -18.3% | — |
| DIALYSIS 422628 | — | — | 2023 | $0.4M | -69.2% | — |
| DIALYSIS 422641 | — | — | 2021 | $0.6M | -63.2% | — |
| DIALYSIS 422642 | — | — | 2021 | $0.7M | -48.8% | — |
| DIALYSIS 422643 | — | — | — | — | — | — |
| DIALYSIS 422663 | — | — | — | — | — | — |
| DIALYSIS 422669 | — | — | 2022 | $1.4M | -12.5% | — |
| DIALYSIS 422674 | — | — | 2022 | $0.7M | -64.2% | — |
| DIALYSIS 422675 | — | — | 2022 | $0.7M | -51.4% | — |
| DIALYSIS 422679 | — | — | 2023 | $1.2M | -80.0% | — |
| DIALYSIS 422686 | — | — | 2024 | $2.0M | -40.5% | 5d |
| DIALYSIS 422910 | — | — | — | — | — | — |
| Dialysis Center of Carolina | Sumter | — | 2024 | $4.1M | +14.4% | 22d |
| Dialysis Clinic Inc-Saluda | Saluda | — | 2025 | $1.0M | -12.9% | — |
| FMC - FREEDOM DIALYSIS CENTER | Florence | — | 2024 | $3.1M | -1.7% | — |
| FMC ANDERSON DIALYSIS CLINIC | Anderson | — | 2024 | $3.1M | +11.6% | — |
| FMC BAMBERG DIALYSIS | Bamberg | — | 2024 | $2.4M | +0.2% | — |
| FMC Black Creek Dialysis Center | Hartsville | — | 2024 | $3.2M | +12.7% | — |
| FMC BMA OF BEAUFORT INC LOW COUNTRY DIALYSIS | Port Royal | — | 2024 | $3.6M | -5.0% | — |
| FMC BMA OF CHESTER INC | Chester | — | 2024 | $2.5M | +11.1% | — |
| FMC CONWAY DIALYSIS CENTER | Conway | — | 2024 | $2.1M | +2.1% | — |
| FMC DARLINGTON DIALYSIS CENTER INC | Darlington | — | 2024 | $2.8M | +6.8% | — |
| FMC DIALYSIS SERVICES ANDREWS | Andrews | — | 2024 | $1.6M | -5.5% | — |
| FMC DIALYSIS SERVICES MURRELLS INLET | Murrells Inlet | — | 2024 | $3.4M | +25.2% | — |
| FMC DIALYSIS SERVICES NORTH MYRTLE BEACH | North Myrtle Beach | — | 2024 | $5.3M | +22.0% | — |
| FMC DIALYSIS SERVICES OF YORK COUNTY | Rock Hill | — | 2024 | $3.8M | +14.2% | — |
| FMC DIALYSIS SERVICES THE MARSHLANDS | Ridgeland | — | 2024 | $4.1M | +22.4% | — |
| FMC FLORENCE DIALYSIS CENTER | Florence | — | 2024 | $2.7M | +7.9% | — |
| FMC HILTON HEAD DIALYSIS CENTER | Hilton Head Island | — | 2024 | $1.4M | -30.7% | — |
| FMC HOLLYWOOD RAVENEL DIALYSIS CLINC | Ravenel | — | 2024 | $2.5M | +12.0% | — |
| FMC KINGSTREE DIALYSIS | Kingstree | — | 2024 | $3.7M | +19.6% | — |
| FMC LORIS DIALYSIS CENTER | Loris | — | 2024 | $2.6M | +14.1% | — |
| FMC MARION | Marion | — | 2024 | $3.3M | +11.7% | — |
| FMC MEADOWLAKE DIALYSIS | Columbia | — | 2024 | $3.3M | +18.4% | — |
| FMC MT PLEASANT DIALYSIS CENTER | Mount Pleasant | — | 2024 | $1.5M | -4.8% | — |
| FMC NRA HOLLY HILL DIALYSIS CENTER | Holly Hill | — | 2024 | $1.3M | -20.2% | — |
| FMC of Fort Mill | Fort Mill | — | 2024 | $10.7M | +29.7% | — |
| FMC OF GEORGETOWN INC | Georgetown | — | 2024 | $3.4M | +0.5% | — |
| FMC OF NEWBERRY | Newberry | — | 2024 | $4.7M | +19.3% | — |
| FMC ORANGEBURG DIALYSIS | Orangeburg | — | 2024 | $3.6M | -2.7% | — |
| FMC PEE DEE DIALYSIS CENTER | Lake City | — | 2024 | $3.5M | +10.6% | — |
| FMC RAI CARE CENTERS CHARLESTON | Charleston | — | 2024 | $6.2M | +11.1% | — |
| FMC RAI CARE CENTERS SUMMERVILLE | Summerville | — | 2024 | $3.9M | +20.3% | — |
| FMC SERVICES OF BELTON HONEA PATH | Honea Path | — | 2024 | $1.5M | -3.4% | — |
| FMC Winyah | Georgetown | — | 2024 | $2.2M | +9.0% | — |
| Fresenius Kidney Care Carnes Crossroads | Summerville | — | 2024 | $1.2M | -13.2% | — |
| FRESENIUS KIDNEY CARE CAROLINA - INTERSTATE PARK | Spartanburg | — | 2024 | $4.8M | +19.0% | 101d |
| Fresenius Kidney Care Florence Home | Florence | — | 2024 | $6.1M | +9.2% | 122d |
| Fresenius Kidney Care Florence Medical Mile | Florence | — | 2024 | $1.7M | -12.8% | — |
| Fresenius Kidney Care Gaston | Gaston | — | 2024 | $1.0M | -46.1% | — |
| Fresenius Kidney Care Orangeburg | Orangeburg | — | 2024 | $1.7M | -23.1% | — |
| FRESENIUS KIDNEY CARE PORT ROYAL | Beaufort | — | 2024 | $1.8M | -6.2% | — |
| Fresenius Kidney Care South Congaree | West Columbia | — | 2024 | $2.3M | +9.9% | — |
| FRESENIUS KIDNEY CARE SPARTANBURG | Spartanburg | — | 2024 | $4.7M | +16.7% | 83d |
| Fresenius Kidney Care The Lakes Dialysis | Columbia | — | 2024 | $1.7M | -4.8% | — |
| Fresenius Medical Care Aiken | Aiken | — | 2024 | $1.9M | +13.5% | — |
| FRESENIUS MEDICAL CARE BENNETTSVILLE | Bennettsville | — | 2024 | $2.2M | +5.0% | — |
| FRESENIUS MEDICAL CARE CAMDEN | Camden | — | 2024 | $3.1M | +23.0% | — |
| FRESENIUS MEDICAL CARE CHARLESTON COUNTY | Mount Pleasant | — | 2024 | $1.8M | +6.3% | — |
| FRESENIUS MEDICAL CARE CHERAW | Cheraw | — | 2024 | $3.0M | +18.9% | — |
| FRESENIUS MEDICAL CARE CHURCH STREET | Florence | — | 2024 | $2.4M | +13.5% | — |
| FRESENIUS MEDICAL CARE COLUMBIA | Columbia | — | 2024 | $3.7M | -5.6% | — |
| Fresenius Medical Care Columbia Home | Columbia | — | 2024 | $4.7M | +12.4% | — |
| FRESENIUS MEDICAL CARE DILLON | Dillon | — | 2024 | $2.5M | -16.2% | — |
| FRESENIUS MEDICAL CARE FAIRFIELD COUNTY | Winnsboro | — | 2024 | $2.2M | +5.1% | — |
| Fresenius Medical Care Fort Lawn | Fort Lawn | — | 2024 | $1.2M | -45.8% | — |
| Fresenius Medical Care Hartsville Home Dialysis | Hartsville | — | 2024 | $1.4M | -10.2% | — |
| FRESENIUS MEDICAL CARE IRMO | Irmo | — | 2024 | $3.3M | +12.9% | — |
| FRESENIUS MEDICAL CARE JOHNSONVILLE | Johnsonville | — | 2024 | $2.0M | +10.8% | — |
| FRESENIUS MEDICAL CARE LEXINGTON | Lexington | — | 2024 | $3.2M | +21.3% | — |
| Fresenius Medical Care Low Country Home Dialysis | Summerville | — | 2024 | $3.5M | +23.1% | 137d |
| FRESENIUS MEDICAL CARE LOWER RICHLAND | Columbia | — | 2024 | $2.6M | -3.1% | — |
| Fresenius Medical Care Manning | Manning | — | 2024 | $4.0M | +23.2% | — |
| FRESENIUS MEDICAL CARE MIDTOWN | Columbia | — | 2024 | $13.1M | +29.8% | — |
| Fresenius Medical Care Moncks Corner | Moncks Corner | — | 2024 | $3.4M | +7.5% | — |
| Fresenius Medical Care Myrtle Beach | Myrtle Beach | — | 2024 | $5.6M | +22.0% | — |
| FRESENIUS MEDICAL CARE NORTH ANDERSON | Anderson | — | 2024 | $5.0M | +12.1% | — |
| FRESENIUS MEDICAL CARE NORTH CHARLESTON | North Charleston | — | 2024 | $3.2M | +8.0% | — |
| Fresenius Medical Care North Star Dialysis | Columbia | — | 2024 | $3.6M | +18.5% | — |
| FRESENIUS MEDICAL CARE OF BATESBURG LEESVILLE | Leesville | — | 2024 | $2.8M | +15.9% | — |
| FRESENIUS MEDICAL CARE OF LEE COUNTY | Bishopville | — | 2024 | $2.3M | +1.2% | — |
| FRESENIUS MEDICAL CARE OF LUGOFF ELGIN | Lugoff | — | 2024 | $1.6M | -1.8% | — |
| FRESENIUS MEDICAL CARE SOUTH COLUMBIA | Columbia | — | 2024 | $3.5M | +21.2% | — |
| FRESENIUS MEDICAL CARE SUMTER | Sumter | — | 2024 | $5.4M | +24.6% | — |
| Fresenius Medical Care Sumter Home | Sumter | — | 2024 | $2.1M | -2.5% | — |
| Fresenius Medical Care Swan Lake Dialysis Center | Sumter | — | 2024 | $2.9M | +12.1% | — |
| Fresenius Medical Care Walterboro | Walterboro | — | 2024 | $2.5M | -5.1% | 1d |
| FRESENIUS MEDICAL CARE WEST COLUMBIA | West Columbia | — | 2024 | $3.1M | +13.7% | — |
| FRESENIUS MEDICAL CARE WEST CONWAY | Conway | — | 2024 | $2.9M | +12.3% | — |
| FRESENIUS OF YORK | York | — | 2024 | $3.3M | +17.1% | — |
| GREENVILLE DIALYSIS CLINIC, LLC | Greenville | — | 2024 | $2.6M | +2.2% | 7d |
| KEOWEE DIALYSIS CENTER LLC | Seneca | — | 2024 | $4.6M | +21.1% | 22d |
| Lexington Kidney Center, LLC | West Columbia | — | 2024 | $3.4M | +1.8% | 6d |
| North Augusta Dialysis Center, LLC | North Augusta | — | 2024 | $5.7M | +18.7% | 24d |
| NORTH MAIN KIDNEY CENTER | Columbia | — | 2024 | $2.9M | +21.6% | 12d |
| Seneca Dialysis Center | Seneca | — | 2024 | $4.6M | +21.1% | 22d |
| USRC Barnwell | Barnwell | — | 2024 | $2.5M | +9.8% | 339d |
| USRC Downtown Easley Dialysis | Easley | — | 2024 | $6.7M | +21.7% | 96d |
| USRC Easley Home Therapies | Easley | — | 2024 | $2.3M | +7.5% | 128d |
| USRC Edgefield | Edgefield | — | 2024 | $1.8M | +25.2% | 414d |
| USRC Gaffney | Gaffney | — | 2024 | $0.3M | — | — |
| USRC GREENVILLE | Greenville | — | 2024 | $4.7M | +6.1% | — |
| USRC HOLLY TREE | Simpsonville | — | 2024 | $4.9M | +15.9% | 86d |
| USRC Lyman Dialysis | Lyman | — | 2024 | $1.3M | -9.8% | — |
| USRC North Aiken Dialysis | Aiken | — | 2024 | $5.3M | +15.8% | 59d |
| USRC PLEASANTBURG DIALYSIS | Greenville | — | 2024 | $2.2M | -12.7% | — |
| USRC PLEASANTBURG HOME | Greenville | — | 2024 | $1.7M | +17.6% | 131d |
| USRC Powderhorn Dialysis | Simpsonville | — | 2024 | $2.3M | +6.2% | — |
| USRC South Aiken Dialysis | Aiken | — | 2024 | $9.7M | +39.2% | 250d |
| USRC Travelers Rest Dialysis | Travelers Rest | — | 2024 | $2.1M | +7.5% | 46d |
